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Module Clinical pharmacology

Внимание! Все тесты в этом разделе разработаны пользователями сайта для собственного использования. Администрация сайта не проверяет возможные ошибки, которые могут встретиться в тестах.
module Clinical pharmacology

Список вопросов теста

Вопрос 1

The use of this drug in osteoarthritis is not recommended due to the presence of the risk of severe adverse reactions and interactions, and it has been shown that its use contributes to the progression of the degenerative process in cartilage. Summarize what kind of drug is it?

 

Варианты ответов
  • A. indomethacin
  • B. diclofenac sodium
  • V. ibuprofen
  • G. Nimesulide
Вопрос 2

specify, captopril is contraindicated in patients:
        

 

Варианты ответов
  • a) with liver cirrhosis
  • b) with chronic renal failure
  • c) with a pulmonary heart
  • d) with diabetes
Вопрос 3

the combination of gentamicin with vancomycin is considered:
 

Варианты ответов
  • a) rational, due to the increase in the antibacterial activity of both drugs;
  • b) irrational due to the risk of high hepatotoxicity;
  • c) irrational due to a decrease in antibacterial activity;
  • g) irrational due to the risk of high neuro-and nephrotoxicity.
Вопрос 4

Specify what includes the basic therapy of the first line of the mild persistent course of bronchial asthma:

 

Варианты ответов
  • a) Low doses of inhaled glucorticosteroids.
  • b) Cromons.
  • c) Anti-leukotriene preparations
  • d) Theophyllines long-acting
Вопрос 5

Which of the antibiotics creates high concentrations in bone tissue:

 

Варианты ответов
  • a) gentamicin
  • b) nalidixic acid
  • c) lincomycin
  • d) erythromycin
Вопрос 6

The combination of gentamicin with which antibiotic gives a pronounced synergism when acting on enterococcus:
 

Варианты ответов
  • a) tetracycline
  • b) lincomycin
  • c) erythromycin
  • d) penicillin
Вопрос 7

The drug of choice for angina in a patient with bradycardia is:


 

Варианты ответов
  • a) amlodipine
  • b) bisoprolol
  • c) verapamil
  • d) diltiazem
Вопрос 8

Similar in the mechanism of action with nitroglycerin is:


 

Варианты ответов
  • a) propranolol
  • b) corinfar
  • c) molsidomine
  • d) verapamil
Вопрос 9

A three-component scheme for eradicationH. Pylori includes:

 

Варианты ответов
  • a) famotidine + omeprazole + amoxicillin
  • b) omeprazole + amoxicillin + clarithromycin
  • c) famotidine + amoxicillin + clarithromycin
  • g) omeprazole + de-nol + famotidine
Вопрос 10

Select the indication for the appointment of antacids with peptic ulcer:

 

Варианты ответов
  • a) are the main drug in eradication schemes
  • b) used to relieve pain and heartburn.
  • c) used for aftercare after the course of eradication
  • g) are used as a bactericidal agent
Вопрос 11

 Indicate one of the important advantages of omeprazole over H2 blockers - histamine receptors:

 

Варианты ответов
  • a) low cost of the drug
  • b) no “withdrawal syndrome”
  • c) inhibits the secretion of hydrochloric acid
  • d) has a cytoprotective effect
Вопрос 12

To avoid “withdrawal syndrome”, H2 - blockers should be discontinued for:
 

Варианты ответов
  • a) 3 days
  • b) 5 days
  • c) 2 weeks
  • d) two months
Вопрос 13

Choose which anti-ulcer drugs can cause hypophosphatemia:


 

Варианты ответов
  • a) aluminum-containing antacids
  • b) bismuth-containing drugs
  • c) proton pump blockers
  • d) H2-histamine blockers
Вопрос 14

Compare: Ipratropia bromide differs from inhaled B2 agonists:


 

Варианты ответов
  • a) longer bronchodilating effect
  • b) a more pronounced bronchodilatory effect
  • c) faster coming effect
  • g) greater effectiveness of relief of an attack of bronchial asthma
Вопрос 15

Choose a rational combination of antihypertensives:

 

Варианты ответов
  • a) nifedipins + бeta-blockers
  • b) adrenergic blockers + verapamil
  • c) IAPP + nifedipins
  • d) ACE inhibitors + angiotensin II receptor blockers
Вопрос 16

Specify the effect of the simultaneous appointment of nifedipine and prazosin:

 

Варианты ответов
  • a) increase in vascular resistance
  • b) increased fluid retention
  • c) increased tachycardia
  • d) hyperlipidemia
Вопрос 17

Answer why the dose of verapamil orally for a sufficient hypotensive effect should be high:
 

Варианты ответов
  • a) due to pronounced presystemic metabolism
  • b) due to the slow onset of effect
  • c) due to a small T 1 \ 2
  • d) due to rapid removal of the drug
Вопрос 18

Highlight which drug can increase the concentration of propranolol:

 

Варианты ответов
  • a) phenobarbital
  • b) cimetidine
  • c) rifampicin
  • d) carvedilol
Вопрос 19

Specify a drug that is not recommended to be used for gout because of its ability to cause hyperuricemia:
 

Варианты ответов
  • A) nitroglycerin
  • B) erythromycin
  • B) propranolol
  • D) hypothiazide
Вопрос 20

Answer, excretion increases in alkaline urine:

 

Варианты ответов
  • a) morphine
  • b) procainamide
  • c) barbiturates
  • d) quinine
Вопрос 21

Highlight a side effect of metformin:

 

Варианты ответов
  • 1) hyperglycemia
  • 2) acute pancreatitis
  • 3) constipation
  • 4) lactate - acidosis
Вопрос 22

Highlight what is not typical for the appointment of insulin:

 

Варианты ответов
  • 1) type 1 diabetes
  • 2) ketoacidotic coma
  • 3) pregnancy in patients with type 2 diabetes
  • 4) hypoglycemic coma
Вопрос 23

1. Analyze and answer: This antibacterial agent belongs to the group of beta-lactam antibiotics. It is used in children with infective endocarditis caused by microorganisms of the family Enterobacteriaceae: in combination with gentamicin. What antibacterial drugs are we talking about?

 

Варианты ответов
  • A. cephalexin
  • B. cefotaxime
  • V. ampicillin
  • G. imipenem
Вопрос 24

Analyze and respond: The mechanism of the bronchodilating action of this drug is due to the weakening or cessation of the interaction of acetylcholine with M-cholinergic receptors at the postsynaptic membrane level. What drug are we talking about?

 

Варианты ответов
  • A. Montelukast
  • B. Salbutamol
  • B. Formoterol
  • G. Tiotropium Bromide
Вопрос 25

Analyze and answer: The drug F is a loop diuretic. Reduces peripheral edema, pulmonary congestion, vascular pulmonary resistance, pulmonary capillary wedging pressure in the pulmonary artery and the right atrium. It is effective at low glomerular filtration rate, and therefore is used to treat hypertension in patients with renal insufficiency. What is the name of the drug F?

 

Варианты ответов
  • A. hydrochlorothiazide
  • B. Furosemide
  • V. clopamide
  • G. Veroshpiron
Вопрос 26

Specify the antibiotic that is the drug of choice in the treatment of infections caused by staph. aureus:
       

Варианты ответов
  • a) penicillin
  • b) gentamicin
  • c) azithromycin
  • g) amoxicillin-clavulanate
Вопрос 27

13. Highlight the active drug against atypical pathogens (mycoplasma, chlamydia, legionella):
        

 

Варианты ответов
  • a) gentamicin
  • b) erythromycin
  • c) ampioks
  • d) chloramphenicol
Вопрос 28

The patient is diagnosed with juvenile rheumatoid arthritis. During the treatment with sulfasalazine, a side effect developed, the development of which is due to the dosing regimen of the drug. Specify which of the following undesirable side reactions when taking sulfasalazine are dose-dependent?
 

Варианты ответов
  • A. leukopenia
  • B. urticaria
  • B. agranulocytosis
  • G. aplastic anemia
Вопрос 29

List the most common side effects of inhaled glucocorticoid forms:
        
        

Варианты ответов
  • a) the development of osteoporosis
  • b) hypercortisolism
  • c) candidiasis of the mouth and pharynx
  • d) arterial hypertension
Вопрос 30

A patient suffering from rheumatoid arthritis for a long time receives NSAIDs. Find a drug shown to this patient to prevent ulceration?
      
     

Варианты ответов
  • a) sucralfat
  • b) gastrotsepin
  • c) ranitidine
  • d) mesoprostol
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